molybdopterin-synthase adenylyltransferase (EC 2.7.7.80)
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molybdopterin-synthase adenylyltransferase
EC Number: 2.7.7.80
Reaction: ATP + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP
Systematic name: ATP:molybdopterin-synthase adenylyltransferase
Other names: MoeB; adenylyltransferase and sulfurtransferase MOCS3
Comments: Adenylates the C-terminus of the small subunit of the molybdopterin synthase. This activation is required to form the thiocarboxylated C-terminus of the active molybdopterin synthase small subunit. The reaction occurs in prokaryotes and eukaryotes. In the human, the reaction is catalysed by the N-terminal domain of the protein MOCS3, which also includes a molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) C-terminal domain.