Enzyme of the Day

Each day Apimba highlights one enzyme from our curated database of biochemical catalysts. The selection is deterministic for the day, so everyone sees the same enzyme until midnight UTC.

molybdopterin-synthase adenylyltransferase

EC Number: 2.7.7.80

Reaction: ATP + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP

Systematic name: ATP:molybdopterin-synthase adenylyltransferase

Other names: MoeB; adenylyltransferase and sulfurtransferase MOCS3

Comments: Adenylates the C-terminus of the small subunit of the molybdopterin synthase. This activation is required to form the thiocarboxylated C-terminus of the active molybdopterin synthase small subunit. The reaction occurs in prokaryotes and eukaryotes. In the human, the reaction is catalysed by the N-terminal domain of the protein MOCS3, which also includes a molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) C-terminal domain.

References: BRENDA, EXPASY, IUBMB, KEGG

Enzyme of the Day for September 26, 2026. Full view · Search database · Wiki search

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