(S)-2-hydroxyglutarate dehydrogenase (EC 1.1.5.13)
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(S)-2-hydroxyglutarate dehydrogenase
EC Number: 1.1.5.13
Reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol
Systematic name: (S)-2-hydroxyglutarate:quinone oxidoreductase
Other names: L-2-hydroxyglutarate dehydrogenase; lhgO (gene name); ygaF (gene name)
Comments: The enzyme, characterized from the bacterium Escherichia coli, contains an FAD cofactor that is not covalently attached. It is bound to the cytoplasmic membrane and is coupled to the membrane quinone pool.