VOLUME XXXVI. Hormone Action (Part A: Steroid Hormones)

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"This volume contains a compilation of techniques, and as such is intended to provide a methodological reference for studies of steroid hormone action. Thyroid hormones are also included in this volume because of their apparent similarities in regard to molecular mechanism of action. Considerations are provided concerning the manner in which hormones circulate in the blood stream and are eventually sequestered in target cells. This leads to description of their interactions with cytoplasmic and nuclear receptors as well as presentation of techniques for purification of the steroid hormone receptor molecules. Methods dealing with the biochemical and biological processes stimulated by steroid hormones are included in addition to methods for assessing hormone metabolism. Although a good deal of work and interest in this field has been at the level of gene transcription and nucleic acid synthesis, such methods have been and will continue to be dealt with in other volumes of this series."