VOLUME 549. Riboswitch Discovery, Structure and Function

Available here.

"These two volumes (Methods in Enzymology 549 and 550) include 40 contributions that outline cutting-edge methods representing a wide spectrum of research questions and scientific themes. The first volume emphasizes natural riboswitches, from their discovery to assessment of their structures and functions. The second volume shifts the focus to applying riboswitches as tools for a variety of applications and as targets for inhibition by potential new antibacterial compounds. A third volume (Methods in Enzymology 553) will appear shortly after these two focusing on computational methods for predicting and evaluating dynamic RNA structures."