VOLUME 514. Ghrelin

Available here.

"Although the discovery of ghrelin is dated back to 1999, it has a long history since 1950s when Dr. Davis reported the gastric cells similar to the pancreatic alpha cells. These A-like cells turned out to be ghrelin cells. The first GHS (growth hormone secretagogue), a synthetic ghrelin mimetic, was discovered in 1976 by Dr. Bowers and led to the identification of the GHS receptor, which was the key strategic molecule for the discovery of ghrelin. Among the authors in this volume, we sincerely thank Dr. Bowers because he is the father of ghrelin and contributes the history before ghrelin discovery. This volume provides descriptions of several aspects of ghrelin, from its structure to clinical applications."